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Hsd11b1tm1Yko
Targeted Allele Detail
Nomenclature
Symbol: Hsd11b1tm1Yko
Name: hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1, Yuri V Kotelevtsev
MGI ID: MGI:2385796
Synonyms: 11beta-HSD-1-, 11beta-HSD1-, HSD1-
Gene: Hsd11b1  Location: Chr1:193221630-193264054 bp, - strand  Genetic Position: Chr1, 97.67 cM
Hsd11b1tm1Yko/Hsd11b1tm1Ykomice show lipid accumulation in the liver

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:37960
Parent Cell Line:  CGR8 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hsd11b1 Mutation:  6 strains or lines available
References
Original:  J:37960 Kotelevtsev YV, et al., Inactivation of 11 beta-hydroxysteroid dehydrogenase type 1 by gene targeting in mice. Endocr Res. 1996;22(4):791-792
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory