About   Help   FAQ
Phenotype Image Detail
Image
Caption Fasting Hsd11b1tm1Yko/Hsd11b1tm1Yko liver shows pronounced lipid accumulation. Shown is Oil red O histology of liver sections from ad lib fed wild-type mice (A), 24 hour fasted wild-type mice (B), ad lib fed Hsd11b1tm1Yko/Hsd11b1tm1Yko (C), and 24 hour fasted Hsd11b1tm1Yko/Hsd11b1tm1Yko mice (D). Liver sections were viewed with a light microscope at x40 magnification. Blue hematoxylin counterstaining indicates nuclei, and red staining indicates fat deposition.
Copyright This image is from Morton NM, J Biol Chem 2001 Nov 2;276(44):41293-300 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:72402
Associated
Alleles
Symbol Name
Hsd11b1tm1Yko hydroxysteroid 11-beta dehydrogenase 1; targeted mutation 1, Yuri V Kotelevtsev
Associated
Genotypes
Allelic Composition Genetic Background
Hsd11b1tm1Yko/Hsd11b1tm1Yko involves: 129P2/OlaHsd * MF1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory