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Targeted Allele Detail
Symbol: Cited2tm1Ycy
Name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; targeted mutation 1, Yu-Chung Yang
MGI ID: MGI:2385355
Synonyms: Cited2-
Gene: Cited2  Location: Chr10:17723228-17725673 bp, + strand  Genetic Position: Chr10, 7.18 cM, cytoband A2
Eye phenotype and exencephaly of Cited2tm1Ycy/Cited2tm1Ycy mice

Show the 3 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:78364
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe entire coding region of the endogenous gene was replaced by a neomycin selection cassette. Transcript was undetected in by Northern blot analysis of total embryonic RNA. (J:78364)
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cited2 Mutation:  10 strains or lines available
ES cell line = R19.

Original:  J:78364 Yin Z, et al., The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10488-93
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory