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Tfr2tm1Slu
Targeted Allele Detail
Nomenclature
Symbol: Tfr2tm1Slu
Name: transferrin receptor 2; targeted mutation 1, St Louis School of Medicine
MGI ID: MGI:2384726
Synonyms: TfR2245x, Tfr2Y245X
Gene: Tfr2  Location: Chr5:137569851-137587481 bp, + strand  Genetic Position: Chr5, 76.57 cM
Perl's staining of liver sections of wild-type and Tfr2tm1Slu/Tfr2tm1Slu mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78360
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Single point mutation
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tfr2 Mutation:  4 strains or lines available
References
Original:  J:78360 Fleming RE, et al., Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10653-8
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/01/2014
MGI 5.18
The Jackson Laboratory