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Targeted Allele Detail
Symbol: Zfa-pstm1Ems
Name: zinc finger protein, autosomal, pseudogene; targeted mutation 1, Elizabeth M Simpson
MGI ID: MGI:2384333
Gene: Zfa-ps  Location: Chr10:52418416-52421835 bp, - strand  Genetic Position: Chr10, 26.71 cM, cytoband B3-B4
Germline Transmission:  Earliest citation of germline transmission: J:85220
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe entire gene was replaced with a PGK-neo cassette inserted by homologous recombination. The absence of transcript was confirmed by Northern blot analysis of homozygous mutant testes. (J:85220)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Zfa-ps Mutation:  22 strains or lines available
Original:  J:85220 Banks KG, et al., Retroposon compensatory mechanism hypothesis not supported: Zfa knockout mice are fertile. Genomics. 2003 Sep;82(3):254-60
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
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