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Targeted Allele Detail
Symbol: Magtm1Mtg
Name: myelin-associated glycoprotein; targeted mutation 1, Dirk Montag
MGI ID: MGI:2384092
Synonyms: Mag-, Mag-Ko, Magnull
Gene: Mag  Location: Chr7:30598601-30614298 bp, - strand  Genetic Position: Chr7, 19.26 cM
Germline Transmission:  Earliest citation of germline transmission: J:19475
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsThe gene was disrupted by insertion of a PGK-neo cassette into exon 5 via homologous recombination. Absence of gene expression was confirmed by Western blot analysis of brain proteins from 26-day-old homozygous mutant animals. Immunohistochemical analysis of sciatic and optic nerve sections from 8-week-old homozygous mutants also failed to detect protein. (J:19475)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mag Mutation:  17 strains or lines available
Original:  J:19475 Montag D, et al., Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin. Neuron. 1994 Jul;13(1):229-46
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory