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Foxb1tm1Blh
Targeted Allele Detail
Nomenclature
Symbol: Foxb1tm1Blh
Name: forkhead box B1; targeted mutation 1, Brigid L Hogan
MGI ID: MGI:2183919
Synonyms: mf3-, mf3tm1blh-
Gene: Foxb1  Location: Chr9:69757710-69760940 bp, - strand  Genetic Position: Chr9, 38.76 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:40034
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region and 5' untranslated sequence were replace by a neomycin selection cassette. Transcript was undetected in the heads of homozygous mutant embryos via whole mount in situ hybridization. (J:40034)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 15 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxb1 Mutation:  8 strains or lines available
References
Original:  J:40034 Labosky PA, et al., The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. Development. 1997 APR;124(7):1263-1274
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory