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Targeted Allele Detail
Symbol: Mapk8ip1tm1Wae
Name: mitogen-activated protein kinase 8 interacting protein 1; targeted mutation 1, Gerard Waeber
MGI ID: MGI:2182967
Synonyms: IB1/JIP-1-
Gene: Mapk8ip1  Location: Chr2:92383676-92401263 bp, - strand  Genetic Position: Chr2, 50.99 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:70600
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 3-8 were replaced with a PGK-neo cassette via homologous recombination. Genotype analysis identified 1 homozygous mutant at 3.5 days post coitum out of 148 embryos analyzed. (J:70600)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk8ip1 Mutation:  13 strains or lines available
Original:  J:70600 Thompson NA, et al., Islet-brain1/JNK-interacting protein-1 is required for early embryogenesis in mice. J Biol Chem. 2001 Jul 27;276(30):27745-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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