About   Help   FAQ
Hist1h1etm1Ais
Targeted Allele Detail
Nomenclature
Symbol: Hist1h1etm1Ais
Name: histone cluster 1, H1e; targeted mutation 1, Art I Skoultchi
MGI ID: MGI:2182777
Synonyms: H1e-
Gene: Hist1h1e  Location: Chr13:23621755-23622502 bp, - strand  Genetic Position: Chr13, 9.83 cM, cytoband A3.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:72858
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region of the gene was replaced with a PGK-neo cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by reverse-phase HPLC analysis of liver histone extracts. (J:72858)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hist1h1e Mutation:  4 strains or lines available
References
Original:  J:72858 Fan Y, et al., Individual somatic h1 subtypes are dispensable for mouse development even in mice lacking the h1(0) replacement subtype. Mol Cell Biol. 2001 Dec;21(23):7933-43
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory