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Targeted Allele Detail
Symbol: Rfngtm1Grid
Name: RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; targeted mutation 1, Tom Gridley
MGI ID: MGI:2182609
Synonyms: Rfngdl
Gene: Rfng  Location: Chr11:120780746-120784207 bp, - strand  Genetic Position: Chr11, 84.53 cM
Germline Transmission:  Earliest citation of germline transmission: J:77247
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin selection cassette replaced genomic sequence encoding amino acids 53 through 332 (the carboxy terminus) of the encoded protein. The deletion includes all the coding sequence for the mature, processed form of the protein. Northern blot analysis revealed that no transcripts expressed from this gene were present in RNA derived from homozygous mice. (J:77247)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rfng Mutation:  11 strains or lines available
Original:  J:77247 Zhang N, et al., Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice. Genesis. 2002 May;33(1):21-8
All:  4 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory