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Cd24atm1Pjln
Targeted Allele Detail
Nomenclature
Symbol: Cd24atm1Pjln
Name: CD24a antigen; targeted mutation 1, P J Nielsen
MGI ID: MGI:2179996
Synonyms: CD24-, HSA-
Gene: Cd24a  Location: Chr10:43579169-43584262 bp, + strand  Genetic Position: Chr10, 23.01 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:76695
Parent Cell Line:  N1 (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe promoter region and exon 1 were replaced with a neo cassette via homologous recombination. Gene transcripts were absent in spleen from homozygous mutant animals as determined by Northern blot analysis. (J:76695, J:76970)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd24a Mutation:  8 strains or lines available
References
Original:  J:76695 Nielsen PJ, et al., Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. Blood. 1997 Feb 1;89(3):1058-67
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory