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Targeted Allele Detail
Symbol: Cd24atm1Pjln
Name: CD24a antigen; targeted mutation 1, P J Nielsen
MGI ID: MGI:2179996
Synonyms: CD24-, HSA-
Gene: Cd24a  Location: Chr10:43579169-43584265 bp, + strand  Genetic Position: Chr10, 23.01 cM
Germline Transmission:  Earliest citation of germline transmission: J:76695
Parent Cell Line:  N1 (ES Cell)
Strain of Origin:  C57BL/6
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe promoter region and exon 1 were replaced with a neo cassette via homologous recombination. Gene transcripts were absent in spleen from homozygous mutant animals as determined by Northern blot analysis. (J:76695, J:76970)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd24a Mutation:  10 strains or lines available
Original:  J:76695 Nielsen PJ, et al., Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. Blood. 1997 Feb 1;89(3):1058-67
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory