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Targeted Allele Detail
Symbol: Syptm1Sud
Name: synaptophysin; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:2179741
Synonyms: syp I deficient
Gene: Syp  Location: ChrX:7504819-7519495 bp, + strand  Genetic Position: ChrX, 3.44 cM, cytoband A-D
Germline Transmission:  Earliest citation of germline transmission: J:33035
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced exon 3 and flanking sequences. Western blot analysis on brain lysates from homozygous mice confirmed that no detectable encoded protein was present. (J:33035)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Syp Mutation:  23 strains or lines available
Original:  J:33035 McMahon HT, et al., Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4760-4
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory