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Cited2tm1Bha
Targeted Allele Detail
Nomenclature
Symbol: Cited2tm1Bha
Name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; targeted mutation 1, Shoumo Bhattacharya
MGI ID: MGI:2179740
Synonyms: Cited2-
Gene: Cited2  Location: Chr10:17723228-17725673 bp, + strand  Genetic Position: Chr10, 7.18 cM, cytoband A2
Magnetic resonance image (MRI) identification of septal, outflow tract and aortic arch malformations in Cited2tm1Bha/Cited2tm1Bha embryos

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:76593
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-neo cassette replaced 2 exons of the gene which coded for the the 5' UTR and the initiation codon. (J:76593)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 39 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Cited2 Mutation:  15 strains or lines available
References
Original:  J:76593 Bamforth SD, et al., Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat Genet. 2001 Dec;29(4):469-74
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory