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Targeted Allele Detail
Symbol: Sv2atm1Baj
Name: synaptic vesicle glycoprotein 2 a; targeted mutation 1, Sandra M Bajjalieh
MGI ID: MGI:2179735
Gene: Sv2a  Location: Chr3:96181151-96195521 bp, + strand  Genetic Position: Chr3, 41.65 cM, cytoband F2
Germline Transmission:  Earliest citation of germline transmission: J:59073
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance gene replaced a genomic fragment including the exon containing the translation initiation codon. Western blot analysis on brain extracts derived from homozygous mice confirmed that no detectable encoded protein was present. (J:59073)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sv2a Mutation:  19 strains or lines available
Original:  J:59073 Crowder KM, et al., Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15268-73
All:  8 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory