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Omptm1Mom
Targeted Allele Detail
Nomenclature
Symbol: Omptm1Mom
Name: olfactory marker protein; targeted mutation 1, Peter Mombaerts
MGI ID: MGI:2179520
Synonyms: Omp-lacZ, OMP-taulacZ, (OMP)-TLZ-
Gene: Omp  Location: Chr7:97792566-97794654 bp, - strand  Genetic Position: Chr7, 53.59 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:36595
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA tau-lacZ-loxP-tk-neo-loxP expression cassette replaced the coding exon and placed the tau-lacZ sequences under control of the endogenous regulatory sequences. Transient expression of Cre recombinase in C57BL/6 blastocysts excised the thymidine kinase and neomycin sequences. Expression of the tau-lacZ fusion protein in heterozygous mutant mice was detected in olfactory axon termini in individual glomeruli. (J:36595)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Omp Mutation:  22 strains or lines available
References
Original:  J:36595 Mombaerts P, et al., Visualizing an olfactory sensory map. Cell. 1996 Nov 15;87(4):675-86
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory