Asb1^tm1Wehi
Targeted Allele Detail

Summary

• Symbol: Asb1^tm1Wehi
• Name: ankyrin repeat and SOCS box-containing 1; targeted mutation 1, Walter and Eliza Hall Institute of Medical Research
• MGI ID: MGI:2178847
• Synonyms: Asb-1 -
• Gene: Asb1 Location: Chr1:91468266-91487311 bp, + strand Genetic Position: Chr1, 46.19 cM
• Alliance: Asb1^tm1Wehi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:71266
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 and most of exon 2 were replaced by a BetaGal-PGK-neo cassette, in which the BetaGal coding region was fused in frame to the third codon of exon 2. Northern analysis from multiple tissues confirmed the lack of endogenous transcript. (J:71266)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asb1 Mutation: 24 strains or lines available

References

• Original: J:71266 Kile BT, et al., Functional analysis of Asb-1 using genetic modification in mice. Mol Cell Biol. 2001 Sep;21(18):6189-97
• All: 2 reference(s)