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Casp3tm1Mak
Targeted Allele Detail
Nomenclature
Symbol: Casp3tm1Mak
Name: caspase 3; targeted mutation 1, Tak W Mak
MGI ID: MGI:2178778
Synonyms: Casp3-, CPP32ex3-
Gene: Casp3  Location: Chr8:46617449-46638706 bp, + strand  Genetic Position: Chr8, 26.39 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:74972
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Casp3 Mutation:  8 strains or lines available
References
Original:  J:74972 Woo M, et al., Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev. 1998 Mar 15;12(6):806-19
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory