About   Help   FAQ
Crhr2tm1Mpsp
Targeted Allele Detail
Nomenclature
Symbol: Crhr2tm1Mpsp
Name: corticotropin releasing hormone receptor 2; targeted mutation 1, Mary P Stenzel-Poore
MGI ID: MGI:2178619
Synonyms: CRF2 KO
Gene: Crhr2  Location: Chr6:55090049-55133016 bp, - strand  Genetic Position: Chr6, 27.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:61510
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe exons encoding transmembrane domains 3-5 and surrounding sequence were replaced with a neo cassette via homologous recombination. (J:61510)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crhr2 Mutation:  15 strains or lines available
References
Original:  J:61510 Coste SC, et al., Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2. Nat Genet. 2000 Apr;24(4):403-9
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory