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Mycntm1Fwa
Targeted Allele Detail
Nomenclature
Symbol: Mycntm1Fwa
Name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived; targeted mutation 1, Frederick W Alt
MGI ID: MGI:2178216
Synonyms: N-myc-
Gene: Mycn  Location: Chr12:12936096-12941914 bp, - strand  Genetic Position: Chr12, 6.14 cM, cytoband A3-B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:3413
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced part of exon 2. Northern blot analysis confirmed absence of wild-type transcripts in homozygous mutant embryos at E10.5. (J:3413)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mycn Mutation:  14 strains or lines available
References
Original:  J:3413 Charron J, et al., Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. Genes Dev. 1992 Dec;6(12A):2248-57
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory