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Targeted Allele Detail
Symbol: Myctm1Brd
Name: myelocytomatosis oncogene; targeted mutation 1, Allan Bradley
MGI ID: MGI:2178196
Synonyms: c-myc -
Gene: Myc  Location: Chr15:61985391-61990374 bp, + strand  Genetic Position: Chr15, 26.19 cM, cytoband D2-D3
Germline Transmission:  Earliest citation of germline transmission: J:4556
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsA neomycin resistance cassette was inserted into the second exon. Western blot analysis on doubly targeted ES cells demonstrated that no detectable protein was expressed from this allele. (J:4556)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myc Mutation:  29 strains or lines available
Original:  J:4556 Davis AC, et al., A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice. Genes Dev. 1993 Apr;7(4):671-82
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory