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Myctm1Brd
Targeted Allele Detail
Nomenclature
Symbol: Myctm1Brd
Name: myelocytomatosis oncogene; targeted mutation 1, Allan Bradley
MGI ID: MGI:2178196
Synonyms: c-myc -
Gene: Myc  Location: Chr15:61985391-61990374 bp, + strand  Genetic Position: Chr15, 26.19 cM, cytoband D2-D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:4556
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin resistance cassette was inserted into the second exon. Western blot analysis on doubly targeted ES cells demonstrated that no detectable protein was expressed from this allele. (J:4556)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myc Mutation:  25 strains or lines available
References
Original:  J:4556 Davis AC, et al., A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice. Genes Dev. 1993 Apr;7(4):671-82
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory