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Engtm1Hma
Targeted Allele Detail
Nomenclature
Symbol: Engtm1Hma
Name: endoglin; targeted mutation 1, Helen M Arthur
MGI ID: MGI:2177822
Synonyms: Eng-
Gene: Eng  Location: Chr2:32646595-32682658 bp, + strand  Genetic Position: Chr2, 22.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:73415
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Eng Mutation:  14 strains or lines available
References
Original:  J:73415 Arthur HM, et al., Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development. Dev Biol. 2000 Jan 1;217(1):42-53
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory