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Pou4f3tm1Rsd
Targeted Allele Detail
Nomenclature
Symbol: Pou4f3tm1Rsd
Name: POU domain, class 4, transcription factor 3; targeted mutation 1, Michael G Rosenfeld
MGI ID: MGI:2176270
Synonyms: Brn3.1-
Gene: Pou4f3  Location: Chr18:42394539-42397249 bp, + strand  Genetic Position: Chr18, 22.58 cM, cytoband B3-E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:33502
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou4f3 Mutation:  5 strains or lines available
Notes
Homozygous mutant mice have a similar phenotype to dreidel mice, which are homozygous for Pou4f3ddl.

Phenotypic Similarity to Human Syndrome: Hereditary Deafness J:207266.

References
Original:  J:33502 Erkman L, et al., Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. Nature. 1996 Jun 13;381(6583):603-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory