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Tg(Alb-cre)21Mgn
Transgene Detail
Nomenclature
Symbol: Tg(Alb-cre)21Mgn
Name: transgene insertion 21, Mark A Magnuson
MGI ID: MGI:2176228
Synonyms: Albcre, Alb-cre, AlbCre, albumin-cre, crAlb, CreALB
Transgene: Tg(Alb-cre)21Mgn  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe transgene contains a 2.34 kb mouse albumin enhancer/promoter (M. Magnuson verified mouse promoter, personal communication), a nuclear localization sequence-modified Cre recombinase gene and a 2.1 kb fragment from the human growth hormone gene. The promoter is active in hepatocyte cells of the liver. 7 copies of the transgene are estimated to be present. (J:51826)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Alb     Summary of all recombinase alleles driven by Alb.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 15 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
References
Original:  J:51826 Postic C, et al., Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase. J Biol Chem. 1999 Jan 1;274(1):305-15
All:  522 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory