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Tg(HLA-B27)30-4Trg
Transgene Detail
Nomenclature
Symbol: Tg(HLA-B27)30-4Trg
Name: transgene insertion 30-4, Joel D Taurog
MGI ID: MGI:2159095
Synonyms: HLA-B27, Tg(HLA-B27)30-4Trg, Tg(HLA*B27)30-4Trg, Tg(HLA-B)30-4Trg
Transgene: Tg(HLA-B27)30-4Trg  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA transgene containing the human HLA-B allele, HLA-B27, was shown to be expressed in spleen cells of mice carrying the transgene. (J:74663)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:74663 Taurog JD, et al., HLA-B27 in inbred and non-inbred transgenic mice. Cell surface expression and recognition as an alloantigen in the absence of human beta 2-microglobulin. J Immunol. 1988 Dec 1;141(11):4020-3
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory