All Phenotypes Tg(HLA-B27)30-4Trg MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(HLA-B27)30-4Trg
transgene insertion 30-4, Joel D Taurog
MGI:2159095

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(HLA-B27)30-4Trg/?	involves: C57BL/6J * NOD	MGI:3723605

Allelic Composition	Tg(HLA-B27)30-4Trg/?
Genetic Background	involves: C57BL/6J * NOD

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(HLA-B27)30-4Trg mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

• mice are significantly protected from diabetes, with an incidence of 5/14 diabetic females at 30 weeks compared to 19/20 non-transgenic controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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