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Targeted Allele Detail
Symbol: Man2a2tm1Mfu
Name: mannosidase 2, alpha 2; targeted mutation 1, Michiko N Fukuda
MGI ID: MGI:2158829
Synonyms: MX-
Gene: Man2a2  Location: Chr7:80349097-80371375 bp, - strand  Genetic Position: Chr7, 45.65 cM, cytoband D2
Germline Transmission:  Earliest citation of germline transmission: J:73658
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced exon 2, which contains the translation initiation site. Western blot analysis using polyclonal antibodies did not detect protein in testes from homozygous mutant mice. (J:73658)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Man2a2 Mutation:  22 strains or lines available
Original:  J:73658 Akama TO, et al., Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science. 2002 Jan 4;295(5552):124-7
All:  3 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory