About   Help   FAQ
Triotm1Mst
Targeted Allele Detail
Nomenclature
Symbol: Triotm1Mst
Name: triple functional domain (PTPRF interacting); targeted mutation 1, Michel Streuli
MGI ID: MGI:2158695
Synonyms: trio-
Gene: Trio  Location: Chr15:27730652-28025848 bp, - strand  Genetic Position: Chr15, 10.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65380
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin cassette was inserted into sequences encoding the amino-terminal GEF domain. Western blot analysis on immunoprecipitates of E14.5 embryonic cells derived from homozygous mice demonstrated that no detectable protein is produced from this allele. (J:65380, J:112170)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trio Mutation:  59 strains or lines available
References
Original:  J:65380 O'Brien SP, et al., Skeletal muscle deformity and neuronal disorder in trio exchange factor-deficient mouse embryos. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12074-8
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/19/2017
MGI 6.10
The Jackson Laboratory