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Targeted Allele Detail
Symbol: Foxj1tm1Slb
Name: forkhead box J1; targeted mutation 1, Steven L Brody
MGI ID: MGI:2158221
Synonyms: FoxJ1-, Foxj1lacZ, HFH-4 -
Gene: Foxj1  Location: Chr11:116221530-116226225 bp, - strand  Genetic Position: Chr11, 81.16 cM
Germline Transmission:  Earliest citation of germline transmission: J:73616
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsThe gene was disrupted using neomycin resistance gene driven by a PGK promoter and fused with a lacZ gene. Insertion of the targeting cassette occurred in the first exon. Homozygous mutant animals did not express mRNA or protein as demonstrated by Northern and Western analysis. (J:73616)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 248 assay results
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxj1 Mutation:  12 strains or lines available
Original:  J:73616 Brody SL, et al., Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice. Am J Respir Cell Mol Biol. 2000 Jul;23(1):45-51
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.21
The Jackson Laboratory