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Csf3rtm1Link
Targeted Allele Detail
Nomenclature
Symbol: Csf3rtm1Link
Name: colony stimulating factor 3 receptor (granulocyte); targeted mutation 1, Daniel C Link
MGI ID: MGI:2156982
Synonyms: GCSFR-
Gene: Csf3r  Location: Chr4:126024550-126044440 bp, + strand  Genetic Position: Chr4, 59.77 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:37618
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 3 - 8, which include the translational initiation site, signal peptide, and the ligand binding domain. (J:37618)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Csf3r Mutation:  32 strains or lines available
References
Original:  J:37618 Liu F, et al., Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice. Immunity. 1996 Nov;5(5):491-501
All:  44 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory