Mbtps1^{Gt(PST115)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Mbtps1^{Gt(PST115)Byg}
• Name: membrane-bound transcription factor peptidase, site 1; gene trap PST115, BayGenomics
• MGI ID: MGI:2156182
• Synonyms: Mbtps1^{Gt(pGT1.8TM)115Wcs}
• Gene: Mbtps1 Location: Chr8:120234895-120285474 bp, - strand Genetic Position: Chr8, 67.85 cM, cytoband E1
• Alliance: Mbtps1^{Gt(PST115)Byg} page

Mutation origin

• Mutant Cell Line: PST115
• Germline Transmission: Earliest citation of germline transmission: J:70273
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1TMpfs
• Gene trap vector pGT1TMpfs was inserted into the gene.
• Inheritance: Recessive
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  PST115	CC144660 ; (MGI Seq Detail)	5' RACE	Chr8:120272722-120272888 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  30 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mbtps1 Mutation: 72 strains or lines available

References

• Original: J:70273 Mitchell KJ, et al., Functional analysis of secreted and transmembrane proteins critical to mouse development. Nat Genet. 2001 Jul;28(3):241-9
• All: 3 reference(s)