All Phenotypes Mbtps1<Gt(PST115)Byg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mbtps1^{Gt(PST115)Byg}
gene trap PST115, BayGenomics
MGI:2156182

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mbtps1^{Gt(PST115)Byg}/Mbtps1^{Gt(PST115)Byg}	involves: 129P2/OlaHsd * C57BL/6	MGI:3029274
ht2	Mbtps1^{Gt(PST115)Byg}/Mbtps1⁺	involves: 129P2/OlaHsd * C57BL/6	MGI:3837829
ht3	Mbtps1^{Gt(PST115)Byg}/Mbtps1^wrt	involves: 129P2/OlaHsd * C57BL/6	MGI:3837828

Allelic Composition	Mbtps1^{Gt(PST115)Byg}/Mbtps1^{Gt(PST115)Byg}
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mbtps1^{Gt(PST115)Byg} mutation (0 available); any Mbtps1 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality at implantation, complete penetrance ( J:70273 )

• all embryos die at the implantation stage

embryo

abnormal germ layer development ( J:70273 )

inner cell mass degeneration ( J:70273 )

• embryos grown in culture fail to maintain the inner cell mass

Allelic Composition	Mbtps1^{Gt(PST115)Byg}/Mbtps1⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mbtps1^{Gt(PST115)Byg} mutation (0 available); any Mbtps1 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:146454 )

• only half the expected number of pups with this genotype are born

Allelic Composition	Mbtps1^{Gt(PST115)Byg}/Mbtps1^wrt
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mbtps1^{Gt(PST115)Byg} mutation (0 available); any Mbtps1 mutation (72 available)
Mbtps1^wrt mutation (2 available); any Mbtps1 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:146454 )

• no compound heterozygote pups are born alive

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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