Fyn^{Gt(PT1-ATG)24Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Fyn^{Gt(PT1-ATG)24Wrst}
• Name: Fyn proto-oncogene, Src family tyrosine kinase; gene trap 24, Wolfgang Wurst
• MGI ID: MGI:2155461
• Synonyms: R.24
• Gene: Fyn Location: Chr10:39245735-39441377 bp, + strand Genetic Position: Chr10, 20.51 cM
• Alliance: Fyn^{Gt(PT1-ATG)24Wrst} page

Mutation origin

• Mutant Cell Line: R.24
• Germline Transmission: Earliest citation of germline transmission: J:31729
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: PT1-ATG Vector Type: gene trap
• Mutation details: The gene trap vector PT1-ATG inserted into the second intron. A fusion transcript was produced that consisted of the first 290bp of the gene fused to lacZ sequences. (J:31729)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fyn Mutation: 39 strains or lines available

References

• Original: J:31729 Forrester LM, et al., An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1677-82
• All: 1 reference(s)