About   Help   FAQ
Hand1tm1Eno
Targeted Allele Detail
Nomenclature
Symbol: Hand1tm1Eno
Name: heart and neural crest derivatives expressed 1; targeted mutation 1, Eric N Olson
MGI ID: MGI:2153824
Synonyms: Hand1-, Hand1KO, Hand1lacZ
Gene: Hand1  Location: Chr11:57828707-57832818 bp, - strand  Genetic Position: Chr11, 35.27 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46384
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA lacZ reporter gene followed by a neomycin resistance expression cassette was inserted in frame at the position of the initiation codon. (J:46384)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 46 assay results
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hand1 Mutation:  3 strains or lines available
References
Original:  J:46384 Firulli AB, et al., Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet. 1998 Mar;18(3):266-70
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/11/2018
MGI 6.12
The Jackson Laboratory