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Msh3tm1Htr
Targeted Allele Detail
Nomenclature
Symbol: Msh3tm1Htr
Name: mutS homolog 3; targeted mutation 1, Hein te Riele
MGI ID: MGI:2151802
Gene: Msh3  Location: Chr13:92211872-92355003 bp, - strand  Genetic Position: Chr13, 47.63 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59561
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 2 was disrupted by insertion of a vector containing the hygromycin resistance gene. (J:59561)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msh3 Mutation:  26 strains or lines available
References
Original:  J:59561 de Wind N, et al., HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat Genet. 1999 Nov;23(3):359-62
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory