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Ahrtm1Gonz
Targeted Allele Detail
Nomenclature
Symbol: Ahrtm1Gonz
Name: aryl-hydrocarbon receptor; targeted mutation 1, Frank J Gonzales
MGI ID: MGI:2151800
Synonyms: AhR-
Gene: Ahr  Location: Chr12:35497979-35534989 bp, - strand  Genetic Position: Chr12, 15.78 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:25048
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 1 was replaced with a neomycin resistance gene. (J:25048)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 22 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ahr Mutation:  74 strains or lines available
References
Original:  J:25048 Fernandez-Salguero P, et al., Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor [see comments]. Science. 1995 May 5;268(5211):722-6
All:  61 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory