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Targeted Allele Detail
Symbol: Hoxd4tm1Bhr
Name: homeobox D4; targeted mutation 1, Richard R Behringer
MGI ID: MGI:2151488
Synonyms: Hoxd-4-
Gene: Hoxd4  Location: Chr2:74711929-74729123 bp, + strand  Genetic Position: Chr2, 44.13 cM, cytoband D
Germline Transmission:  Earliest citation of germline transmission: J:25267
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsInsertion of a neomycin cassette into sequences encoding the homeodomain. RNAse protection assays did not detect any transcript from this allele in total RNA from E11 embryos or adult kidney or testis tissue derived from homozygous mice. (J:25267)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 12 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxd4 Mutation:  6 strains or lines available
Original:  J:25267 Horan GS, et al., Mutations in paralogous hox genes result in overlapping homeotic transformations of the axial skeleton: evidence for unique and redundant function. Dev Biol. 1995 MAY;169(1):359-372
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory