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Hoxc8tm1Phb
Targeted Allele Detail
Nomenclature
Symbol: Hoxc8tm1Phb
Name: homeobox C8; targeted mutation 1, Philippe Brulet
MGI ID: MGI:2149030
Synonyms: Hox-3.1-, Hoxc-8-, Hoxc-8lacZ
Gene: Hoxc8  Location: Chr15:102990607-102994111 bp, + strand  Genetic Position: Chr15, 58.05 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:590
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsInsertion of a lacZ gene and deletion of codons 2-42 in the coding region. A HOXC8-beta galactosidase fusion protein is expressed from this allele. (J:590)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 107 assay results
In Structures Affected by this Mutation: 12 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxc8 Mutation:  0 strains or lines available
References
Original:  J:590 Le Mouellic H, et al., Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene. Cell. 1992 Apr 17;69(2):251-64
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory