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Targeted Allele Detail
Symbol: Bmp6tm1Rob
Name: bone morphogenetic protein 6; targeted mutation 1, Elizabeth J Robertson
MGI ID: MGI:2136985
Gene: Bmp6  Location: Chr13:38345716-38500314 bp, + strand  Genetic Position: Chr13, 18.15 cM
Germline Transmission:  Earliest citation of germline transmission: J:48561
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA ~1 kb genomic fragment containing 84 bp of exon 2 was replaced with a neomycin selection cassette. These sequences encode a portion of the pro-polypeptide region. RNAse protection assays on total RNA derived from kidney and brain of homozygous mice demonstrated that no detectable transcript was produced from this allele. (J:48561)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Bmp6 Mutation:  13 strains or lines available
Original:  J:48561 Solloway MJ, et al., Mice lacking Bmp6 function. Dev Genet. 1998;22(4):321-39
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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