Phox2b^Dilp1
Chemically induced Allele Detail

Summary

• Symbol: Phox2b^Dilp1
• Name: paired-like homeobox 2b; dilated pupils 1
• MGI ID: MGI:1934628
• Synonyms: Gena269
• Gene: Phox2b Location: Chr5:67251740-67256469 bp, - strand Genetic Position: Chr5, 35.95 cM
• Alliance: Phox2b^Dilp1 page

Mutation origin

• Strain of Origin: (C3H/HeN x BALB/cAnN)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at Harwell. A T to G substitution in codon 44 of exon 1 introduces a premature stop codon. (J:91199)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phox2b Mutation: 25 strains or lines available

References

• Original: J:75964 Thaung C, et al., Novel ENU-induced eye mutations in the mouse: models for human eye disease. Hum Mol Genet. 2002 Apr 1;11(7):755-67
• All: 2 reference(s)