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C5ar1tm1Cge
Targeted Allele Detail
Nomenclature
Symbol: C5ar1tm1Cge
Name: complement component 5a receptor 1; targeted mutation 1, Craig Gerard
MGI ID: MGI:1934246
Synonyms: C5aR-, C5aRKO
Gene: C5ar1  Location: Chr7:15980668-15993465 bp, - strand  Genetic Position: Chr7, 8.77 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69177
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA PGK-neomycin resistance cassette replaced the entire coding region of the gene. Northern analysis of bone marrow cells did not detect expression in homozygous mutant mice. (J:69177)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any C5ar1 Mutation:  20 strains or lines available
References
Original:  J:69177 Hopken UE, et al., The C5a chemoattractant receptor mediates mucosal defence to infection. Nature. 1996 Sep 5;383(6595):86-9
All:  131 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory