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Cd36tm1Mfe
Targeted Allele Detail
Nomenclature
Symbol: Cd36tm1Mfe
Name: CD36 molecule; targeted mutation 1, Maria Febbraio
MGI ID: MGI:1931790
Synonyms: Cd36-, CD36KO, CD36 KO, FAT/CD36-
Gene: Cd36  Location: Chr5:17781690-17888801 bp, - strand  Genetic Position: Chr5, 8.11 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:56081
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin cassette replaced a 1kb fragment including the transcription start site. (J:56081)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 15 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd36 Mutation:  19 strains or lines available
References
Original:  J:56081 Febbraio M, et al., A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J Biol Chem. 1999 Jul 2;274(27):19055-62
All:  156 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory