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Ifngr2tm1Pbro
Targeted Allele Detail
Nomenclature
Symbol: Ifngr2tm1Pbro
Name: interferon gamma receptor 2; targeted mutation 1, Paul B Rothman
MGI ID: MGI:1930965
Synonyms: IFN-gammaR2 -, IFNgammaRBnull, Ifngr2tm1Cmb
Gene: Ifngr2  Location: Chr16:91547072-91565169 bp, + strand  Genetic Position: Chr16, 53.07 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:48016
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of the second coding exon with a neomycin gene. (J:48016)
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ifngr2 Mutation:  7 strains or lines available
References
Original:  J:48016 Lu B, et al., Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8233-8
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory