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Targeted Allele Detail
Symbol: Nrg1tm1Cbm
Name: neuregulin 1; targeted mutation 1, Carmen Birchmeier
MGI ID: MGI:1928489
Synonyms: neuregulindelta7-9, Nrg-
Gene: Nrg1  Location: Chr8:31818028-31918203 bp, - strand  Genetic Position: Chr8, 18.75 cM
Germline Transmission:  Earliest citation of germline transmission: J:29971
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance gene replaces exons 7, 8 and 9, which encode the carboxy-terminus of the EGF domain of all known Ngf1 variants. (J:29971)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nrg1 Mutation:  5 strains or lines available
Original:  J:29971 Meyer D, et al., Multiple essential functions of neuregulin in development [see comments] [published erratum appears in Nature 1995 Dec 14;378(6558):753]. Nature. 1995 Nov 23;378(6555):386-90
All:  19 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory