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Targeted Allele Detail
Symbol: Grin2dtm1Mim
Name: glutamate receptor, ionotropic, NMDA2D (epsilon 4); targeted mutation 1, Masayoshi Mishina
MGI ID: MGI:1928298
Synonyms: GluR epsilon4
Gene: Grin2d  Location: Chr7:45481307-45520708 bp, - strand  Genetic Position: Chr7, 29.54 cM
Germline Transmission:  Earliest citation of germline transmission: J:28825
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsThe exon encoding the M4 putative transmembrane segment was interrupted by the insertion of a neomycin cassette. (J:28825)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grin2d Mutation:  20 strains or lines available
Original:  J:28825 Ikeda K, et al., Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel. Brain Res Mol Brain Res. 1995 Oct;33(1):61-71
All:  25 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.21
The Jackson Laboratory