About   Help   FAQ
Stat3tm1Aki
Targeted Allele Detail
Nomenclature
Symbol: Stat3tm1Aki
Name: signal transducer and activator of transcription 3; targeted mutation 1, Shizuo Akira
MGI ID: MGI:1926814
Synonyms: Stat3-
Gene: Stat3  Location: Chr11:100885098-100939540 bp, - strand  Genetic Position: Chr11, 63.82 cM
Histological analysis of wild type and Stat3tm1Aki/Stat3tm1Aki embryos

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:40106
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced 3.0kb of sequence containing exons 20-22. (J:40106)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Stat3 Mutation:  46 strains or lines available
References
Original:  J:40106 Takeda K, et al., Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3801-4
All:  51 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/19/2017
MGI 6.10
The Jackson Laboratory