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| Caption | Wild type embryos (A,C,E & G) and Stat3tm1Aki/Stat3tm1Aki embryos (B,D,F & H) at E6.0 (A & B), E6.5 (C & D), E7.0 (E & F), and E7.5 (G & H). Note the rapid degeneration of the homozygous mutant embryos from E6.5 to E7.5. Mutant embryos formed a two-layered egg cylinder at E6.0 (B) but were degenerated rapidly and resorbed completely by E7.5 (D, F & H). Abbreviations: embryonic ectoderm (ee); mesoderm (m); proamniotic cavity (pac); visceral endoderm (ve). Scale bars: a-f: 40um; g & h: 100um | ||||
| Copyright | This image is from Takeda K, Proc Natl Acad Sci U S A 1997 Apr 15;94(8):3801-4. Copyright 1997 National Academy of Sciences, U.S.A. J:40106 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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