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Tg(Wnt1)1Hev
Transgene Detail
Summary
Symbol: Tg(Wnt1)1Hev
Name: transgene insertion 1, Harold E Varmus
MGI ID: MGI:1890080
Synonyms: line 303, MMTV-wnt, MMTV-Wnt1, MMTV-Wnt-1, Wnt-1
Transgene: Tg(Wnt1)1Hev  Location: unknown  
Alliance: Tg(Wnt1)1Hev page
Transgene
origin
Strain of Origin:  C57BL/6 x SJL
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Wnt1)1Hev expresses 1 gene
 
Mutation detailsWnt1 is driven by the mouse mammary tumor virus (MMTV). The construct resembles alleles found in virus-induced tumors. (J:28473)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Tumor Data
List all tumor models in MMHCdb carrying Tg(Wnt1)1Hev
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:28473 Tsukamoto AS, et al., Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell. 1988 Nov 18;55(4):619-25
All:  108 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory