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Chrna4tm1Dra
Targeted Allele Detail
Nomenclature
Symbol: Chrna4tm1Dra
Name: cholinergic receptor, nicotinic, alpha polypeptide 4; targeted mutation 1, John Drago
MGI ID: MGI:1888964
Gene: Chrna4  Location: Chr2:181018380-181043546 bp, - strand  Genetic Position: Chr2, 103.54 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64208
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin gene was inserted into the fifth exon. (J:64208)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chrna4 Mutation:  8 strains or lines available
References
Original:  J:64208 Ross SA, et al., Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse. J Neurosci. 2000 Sep 1;20(17):6431-41
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory