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Tapbptm1Luc
Targeted Allele Detail
Nomenclature
Symbol: Tapbptm1Luc
Name: TAP binding protein; targeted mutation 1, Luc van Kaer
MGI ID: MGI:1888941
Synonyms: Tpn-
Gene: Tapbp  Location: Chr17:34138452-34148264 bp, + strand  Genetic Position: Chr17, 17.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64177
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Insertion of a neomycin resistance cassette into the fourth exon. (J:64177)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tapbp Mutation:  16 strains or lines available
References
Original:  J:64177 Grandea AG 3rd, et al., Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice. Immunity. 2000 Aug;13(2):213-22
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory