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Pmp22Tr-2H
Chemically induced Allele Detail
Summary
Symbol: Pmp22Tr-2H
Name: peripheral myelin protein 22; trembler 2 Harwell
MGI ID: MGI:1862011
Synonyms: Gena57, GENA 57, Tr-m2H, Y153TER
Gene: Pmp22  Location: Chr11:63019808-63050373 bp, + strand  Genetic Position: Chr11, 38.99 cM
Alliance: Pmp22Tr-2H page
Mutation
origin
Strain of Origin:  BALB/cAnNCrl
Project Collection: Harwell ENU Mutagenesis
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis allele involves an A to T transversion at position 459 producing a premature stop codon at residue 153 deleting the last seven amimo acids of Pmp22 protein. (J:63755)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pmp22 Mutation:  32 strains or lines available
References
Original:  J:63816 Nolan PM, et al., A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet. 2000 Aug;25(4):440-3
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory